Acetylsalicylic acid (acetylsalicylic acid, ASA), better known as aspirin (aspirin), is one of the popular painkillers. The global annual aspirin new beauty magazine 2011 consumption reaches around 40,000 tonnes, representing approximately 120 billion tablets new beauty magazine 2011 of 300 mg [Ref. 2]. In the US it is estimated that the annual consumption reaches of 16,000 tons.
Aspirin is used to treat a wide variety of health problems: As a general analgesic and antipyretic (2-6 tablets a day), as a preventive cerebral thrombosis (one tablet daily) in rheumatic fever and arthritis. Also take preventive new beauty magazine 2011 against heart attacks.
The wide range of pharmaceutical applications of aspirin complicate the investigation of the mechanism of action and only after 1970 formulated the hypothesis that aspirin and corresponding to that drugs inhibit the synthesis of certain substances involved in pain generation mechanisms and inflammation [Ref. 2b]. "For this publication regarding new beauty magazine 2011 this valuable substance, I have other motives, beyond new beauty magazine 2011 hope to qualify for a just and comprehensive test on each variety in each case and situation, and maybe one day the world may benefit from this "
In the Old Testament reference to the therapeutic properties of poplar. The father of medicine, Hippocrates (460-377 BC) used a bitter powder from the bark of willow and poplar or willow herb tea leaves to relieve patients new beauty magazine 2011 from pain and fever. Affluent patients of ancient times they ordered infusions poplar bark (a broth prepared by soaking the bark of these trees with vinegar) to deal with sciatica and arthritis pains.
The great doctor new beauty magazine 2011 of the Graeco-Roman world Claudius Galen (129-199 AD) studied the antiseptic properties of the extracts new beauty magazine 2011 of the bark of trees and their healing wounds and ulcers. Medicinal products based on willow or poplar used by the Chinese, as well as the American Indians to treat wounds, rheumatism, colds and headaches. The Pedanius Dioscorides (40-90 AD) granted extracts poplar leaves (in mixture with pepper and wine) for the treatment of colic pain. Gaius Plinius Secundus (23-79 AD), in his book Natural is Historia, refers to some substances (obviously derivatives of salicylic acid) prepared from powdered bark of willow or poplar.
In 1757, the 'Englishman clergyman Edmund Stone brought forth the healing properties of the bark of the willow. He knew that many parishioners, who suffered from rheumatism, using extracts to soothe new beauty magazine 2011 the pains of illness. The bitter taste of the crust was reminiscent of the taste of the bark of the tree of Peru t th Peruvian Cinchona officinales (pharmaceutical cinchona), from which were producing an expensive drug (quinine) for the treatment of fever in patients new beauty magazine 2011 with malaria and apparently assumed a correlation . The Stone presented at the Royal Society for his work on the analgesic properties of this willow bark extracts, which aroused the interest of the medical world. Then sought an effective analgesic drug to replace this laudanum (opium preparation), the sole active analgesic that era. The laudanum had many side effects and the frequent use lead to addiction.
During the Napoleonic Wars (1803-1815), because of the naval blockade, imports quinine from South America were significantly reduced. Prices of quinine had become prohibitive, and so sought alternative sources or other drugs with similar antipyretic properties. Then it was about to chemists and pharmacists began to show great interest in the properties of the bark extracts of willow and poplar.
Hippocrates new beauty magazine 2011 recommends sheets and shavings new beauty magazine 2011 from the bark of willow as analgesics and antipyretics drugs 1763 Announcement of Pastor Edmund Stone, before the Royal Society, the potential benefits new beauty magazine 2011 from the use of the bark of willow
Aspirin is available without prescription in tablet form
The John Vane theorizes that perhaps aspirin acts by inhibiting prostaglandin formation (a) The leaves and flowers of willow s. (B) Salix Alba "Tristis": White "sad" Willow, better known as crying. (C) Trunk of willow. T he 1829 Henri Leroux isolated 30 g salicin from willow bark 1,5 kg. (A)
(C) In 1828, the Pharmacological Institute in Munich, Professor of Pharmacy J ohann A. Buchner isolated from willow bark extract a very small amount
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